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(500-428) also adopted a terrestrial slime account, although Anaxagoras thought that the germs (seeds) of plants existed in the air from the beginning, and of animals in the ether.

All these accounts rely on the innate (or natural; the Greek word is phusis, from which we get "physics") properties of the elements of the universe. In (384-322) we get the most sophisticated of all these Greek views.

He believed that everything arose out of the elemental nature of the universe, which he called the "apeiron" or "unbounded".

As part of his overall attempt to give natural explanations of things that had previously been ascribed to the agency of the gods, such as thunder, the heavens, and the earth, he gave the following account of life.

Yet, in his lifetime, he was the object of intense opposition by almost the entire biological establishment, because of his own opposition to spontaneous generation and to Darwinism.

It was only his persistence and sound experimental and analytical procedures that finally compelled most biological and medical scientists to give up their ideas of the naturalistic origin of life and their treatment of disease as based on this notion.

Louis Pasteur is one of the greatest names in the history of science and medicine, chiefly because of his establishment of the germ theory of disease and his conclusive demolition of the then-prevalent evolutionary concept of spontaneous generation. He was the first to explain the organic basis and control of fermentation, and as his research led him more and more into bacteriology, he isolated a number of disease-producing organisms and developed vaccines to combat them - notably the dread diseases of rabies, diptheria, anthrax, and others - as well as the processes of pasteurization and sterilization.

He undoubtedly made the greatest contribution of any one man to the saving of human lives, and most scientists today would say that he was the greatest biologist of all time.

Could I but know all, I would have the faith of a Breton peasant woman." of life arising in simple form from nonlife by way of a long and propitious series of chemical steps/selections.

In particular, they did not show that life cannot arise once, and then evolve.

From the facts above enumerated it is quite proved that certain fishes come spontaneously into existence, not being derived from eggs or from copulation.

Such fish as are neither oviparous nor viviparous arise all from one of two sources, from mud, or from sand and from decayed matter that rises thence as a scum; for instance, the so-called froth of the small fry comes out of sandy ground.

He thought there were four elements and a fifth essence later called the "quintessence" or "ether" that occurred only beyond the moon, in the heavens.