1560 - Iroquoian tribes south of the Great Lakes, at war with each other and surrounded by more numerous Algonquian enemies, are on the verge of extinction.The Iroquois Confederacy, the League of the Five Nations, is founded by Deganawidah and Hiawatha. 1600 - The name "Hurons" is given to the Wyandots of the Huron Confederacy by the French.
August 15; a Spanish military expedition from Santa Fe and their Apache allies are defeated by the Pawnee and their French allies near the principal Pawnee village at the forks of the Platte in present Nebraska. 1730 - While retaining their settlements in the Detroit area, many Wyandots migrate southward and settle on the south shore of Lake Erie.They gradually assume sovereignty over all the Ohio country between the Great Lakes and the Miami River.At the invitation of Sieur Antoine de la Mothe Cadillac, Wyandots move south from Michilimackinac to settle in the vicinity of the new fort, but pro- and anti-French (anti-Catholic) divisions persist.Cadillac himself is hostile toward the Jesuits and their missionary efforts.1709-1742 - The Delaware gradually move in small groups from the Delaware River valley to lands controlled by the Iroquois on the West Branch of the Susquehanna in central Pennsylvania.Already at war with other Iroquoian tribes, the Wyandots begin to move west.1541 - May 8; Soto reaches the Mississippi River, having marched overland from the Floridas.
The brutal behavior of the Spanish has a devastating effect on the tribes of the southeast; perhaps coincidently, Mississippian culture enters a rapid decline.c.With his followers he leaves Detroit to establish a new village at Lower Sandusky (present Fremont, Ohio).With his followers he leaves Detroit to establish a new village at Lower Sandusky (present Fremont, Ohio).1744 - August 8; Fort de la Trinite, popularly called Fort de Cavagnial, is established by the French on the west bank of the Missouri River near the principal Kansa village, just north of the present Fort Leavenworth.A Shawnee colony called the Savannah is in South Carolina, where they form a buffer between the Cherokee and the Catawba.1652-c.1665 - The Wyandots and Ottawa move inland from Green Bay to the Mississippi River, then drift north to Chequamegon on Lake Superior in Sioux country, where they resume fur trade with the French.1653-1656 - The Erie lose a protracted war with the Iroquois. Ignace to find the great river described by the Illinois Indians.They reach the Mississippi on June 17, and the mouth of the Arkansas a month later, where they turn back after learning there are Spanish in the area of the present New Orleans.1680 - August 21; Pueblo Indians take possession of Santa Fe after driving out the Spanish.The successful revolt temporarily creates a power vacuum in western North America, which the French are quick to exploit.1682 - April 9; Rene Robert Cavelier, Sieur de La Salle, having descended the full length of the Mississippi with an exploring party of 23 Frenchmen and 31 Indians, claims all of the lands drained by the river and its tribu-taries for France and names it Louisiana.